1995年，非小细胞肺癌协作组（Non-small Cell Lung Cancer Collaborative Group）发表了一项具有里程碑意义的荟萃分析，包括8项随机试验，这些试验对采用化疗和无治疗或最佳支持治疗作为转移性非小细胞肺癌（NSCLC）的一线治疗进行了比较1。这项荟萃分析不仅显示未经治疗的NSCLC患者结局不良（1年总生存率为5%），而且还显示以顺铂为基础的化疗可影响NSCLC的自然病程（1年总生存率为15%）。
作者信息
Joan H. Schiller, M.D.
From the Inova Schar Cancer Institute, Fairfax, VA.
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