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High-Flow Oxygen with Capping or Suctioning for Tracheostomy Decannulation

Gonzalo Hernández Martínez ... 呼吸系统疾病 • 2020.09.10
• 堵管试验推迟了气管切开患者的拔管时间 • 对危重机械通气患者采取非镇静或浅镇静的比较 • 重症监护病房内机械通气患者的镇静措施是否应取消









本试验纳入了330例患者,患者的平均(±SD)年龄为58.3±15.1岁,68.2%为男性。共计161例患者被分配至对照组,169例被分配至干预组。干预组至拔管的时间比对照组短(中位数,6日[四分位距,5~7] vs. 13日[四分位距,11~14];绝对差异,7日[95% CI,5~9])。干预组的肺炎和气管支气管炎发生率低于对照组,住院时长也比对照组短。两组的其他次要结局相似。





Gonzalo Hernández Martínez, M.D., Ph.D., Maria-Luisa Rodriguez, M.D., Maria-Concepción Vaquero, M.D., Ramón Ortiz, M.D., Ph.D., Joan-Ramon Masclans, M.D., Ph.D., Oriol Roca, M.D., Ph.D., Laura Colinas, M.D., Ph.D., Raul de Pablo, M.D., Ph.D., Maria-del-Carmen Espinosa, M.D., Ph.D., Marina Garcia-de-Acilu, M.D., Cristina Climent, M.D., and Rafael Cuena-Boy, M.D.
From Virgen de la Salud University Hospital (G.H.M., M.-L.R., L.C.) and the Research Unit, Medical Council (R.C.-B.), Toledo, Ramón y Cajal University Hospital (M.-C.V., R.P.) and Ciber Enfermedades Respiratorias, Health Institute Carlos III (O.R.), Madrid, Ciudad Real University Hospital and Ciudad Real University, Ciudad Real (R.O., M.-C.E.), Medical Research Mar Institute (J.-R.M.), the Critical Care Department, Autònoma de Barcelona University (J.-R.M., M.G.-A.), Del Mar University Hospital (J.-R.M., C.C.), Vall d’Hebron Research Institute (O.R.), and Vall d’Hebron University Hospital (O.R., M.G.A.), Barcelona, and Alcala University, Alcalá de Henares (R.P.) — all in Spain. Address reprint requests to Dr. Hernández Martínez at the Department of Critical Care Medicine, Virgen de la Salud University Hospital, Tenerife No. 40, Fl. 2, Rm. D, 28039 Madrid, Spain, or at ghernandezm@telefonica.net.



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