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女性的生育力保存
Fertility Preservation in Women


Jacques Donnez ... 妇产科和儿科 • 2017.10.26
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• 第40届圣安东尼奥乳腺癌年度研讨会

女性生育力保存的挑战和机遇

 

李薇薇,戴善军,刘笑聪,郭艺红*

郑州大学第一附属医院生殖与遗传专科医院

*通讯作者

 

随着生育观念的改变和医学技术的进步,健康女性平均生育年龄推迟,年轻恶性肿瘤患者生存率不断提高,生育需求增加。生育力保存为这些女性带来了再生育的希望,对其关注度也日益提高。

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近年来,由于肿瘤和非肿瘤原因以及个人原因对生育力保存的需求急剧增加1,满足这一需求将在未来几年成为重大挑战1。目前,只有胚胎冷冻保存和促排卵后的成熟卵母细胞冷冻保存是美国生殖医学学会(American Society for Reproductive Medicine)认可的生育力保存方法2。然而,许多专家认为,现在有足够的证据支持将卵巢组织冷冻保存作为正规有效的生育力保存技术,而不仅仅是作为一种实验性方法1,3

在所有可用的生育力保存手段中1,应用玻璃化冷冻(极速冷冻)方法的卵母细胞冷冻保存效果最好,不仅对患良性疾病或者因个人原因选择保存生育力的妇女适用,而且对患癌症的妇女(可暂缓治疗的)亦同样适用。卵巢组织冷冻保存则专门针对青少年和癌症治疗不能推迟的患者1,3。本综述重点阐述这两种生育力保存技术的适应证和结果。





作者信息

Jacques Donnez, M.D., Ph.D., and Marie-Madeleine Dolmans, M.D., Ph.D.
From Société de Recherche pour l’Infertilité and Université Catholique de Louvain (J.D.), and Pôle de Gynécologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, and the Department of Gynecology, Cliniques Universitaires Saint-Luc (M.-M.D.) — all in Brussels. Address reprint requests to Dr. Donnez at Société de Recherche pour l’Infertilité, Ave. Grandchamp 143, 1150 Brussels, Belgium, or at jacques.donnez@gmail.com.

 

参考文献

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