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Diabetic Foot Ulcers and Their Recurrence

David G. Armstrong ... 糖尿病 • 2017.06.15
• 局部氧疗对糖尿病足溃疡是否有效 • 下肢溃疡的评估与管理 • 高压氧对于治疗慢性糖尿病足溃疡无效

影响下肢的糖尿病并发症常见、复杂而又花费巨大。糖尿病足溃疡是最广为人知的并发症。一项在英国西北部进行的社区研究中,在筛选阶段,糖尿病患者中活动性足溃疡的患病率为1.7%,年发病率为2.2%1。以下人群的年发病率更高:在作为美国老年医疗保险(Medicare)受益人的糖尿病人群中发病率为6.0%,在美国退伍军人的糖尿病人群中发病率为5.0%,在全球糖尿病患者人群中的发病率为6.3%2-4。根据2015年国际糖尿病联盟(International Diabetes Federation)5的患病率数据估计,每年全球发生糖尿病足溃疡的人数约为910万~2,600万。当然,患糖尿病并有足溃疡史的患者比例高于患活动性溃疡的患者比例;有3.1%~11.8%的糖尿病患者,或全球1,290万~4,900万,美国100万~350万的糖尿病患者有足溃疡史1,5-7。糖尿病足溃疡的终生发病率据过去估计约为糖尿病患者中的15%~25%8,但考虑到新的数据,实际可能会影响19%~34%的糖尿病患者(具体计算见补充附录,补充附录与本文全文可在NEJM.org获取)。


David G. Armstrong, D.P.M., M.D., Ph.D., Andrew J.M. Boulton, M.D., and Sicco A. Bus, Ph.D.
From the Southern Arizona Limb Salvage Alliance (SALSA), Department of Surgery, University of Arizona College of Medicine, Tucson (D.G.A.); Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom (D.G.A., A.J.M.B.); and the Department of Rehabilitation Medicine, Academic Medical Center, University of Amsterdam, and Amsterdam Movement Sciences — both in Amsterdam (S.A.B.).Address reprint requests to Dr. Armstrong at SALSA, Department of Surgery, University of Arizona College of Medicine, 1501 N. Campbell Ave., Tucson, AZ 85724, or at armstrong@usa.net.



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