严重急性呼吸综合征冠状病毒2（SARS-CoV-2）是2019冠状病毒病（COVID-19）的病原体，其引起了全球性大流行。阻断其传播有赖于采取药物和非药物的联合干预措施。最初的SARS-CoV-2预防措施包括社交疏远、佩戴口罩、环境卫生和洗手1。预防SARS-CoV-2感染最重要的药物干预措施可能是接种疫苗，但利用现有药物进行短期预防是一种可以立即投入应用的方法。
一些研究人员在推动氯喹和羟氯喹用于治疗和预防多种微生物感染，包括SARS-CoV 2。体外试验发现羟氯喹可以抑制SARS-CoV-2复制3。一些观察性研究表明，羟氯喹治疗COVID-19有一定疗效，但其他治疗性试验则报告了不同结果4。
作者信息
Myron S. Cohen, M.D.
From the Institute for Global Heath and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill.
参考文献
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