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Long-Term Complications in Youth-Onset Type 2 Diabetes

TODAY Study Group* 糖尿病 妇产科和儿科 • 2021.07.29
• 青少年2型糖尿病患者维持血糖控制的临床试验












在青少年发病的2型糖尿病患者中,并发症(包括微血管并发症)风险随时间推移不断增加,大多数参与者在成年早期已出现并发症。并发症在少数人种和族群中,以及在有高血糖、高血压和血脂异常的患者更为多发(由美国国立糖尿病、消化系统疾病和肾脏疾病研究所[National Institute of Diabetes and Digestive and Kidney Diseases]等资助,在ClinicalTrials.gov注册号为NCT01364350和NCT02310724)。


TODAY Study Group*
From the University of Colorado Anschutz Medical Campus, Children’s Hospital Colorado, Aurora (P.B., P.Z.); George Washington University, Rockville, MD (K.L.D., B.T.); Yale University, New Haven, CT (S.C.); Case Western Reserve University, Rainbow Babies and Children’s Hospital, Cleveland (R.G.-K.); the Massachusetts General Hospital Diabetes Center, Harvard Medical School, Boston (D.M.N.); the University of Oklahoma Health Sciences Center, Oklahoma City (J.T.); and Washington University School of Medicine, St. Louis (N.H.W.). Address reprint requests to Dr. Drews at the Biostatistics Center, George Washington University, 6110 Executive Blvd., Suite 750, Rockville, MD 20852, or at kdrews@bsc.gwu.edu. *The members of the TODAY Study Group are listed in the Supplementary Appendix, available at NEJM.org.



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