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HIV-Associated Cancers and Related Diseases

Robert Yarchoan ... 传染病 肿瘤 • 2018.03.15

纽约和加利福尼亚州有同性性行为的男性群体中肺囊虫肺炎及卡波西肉瘤病例的密集出现是获得性免疫缺陷综合征(简称“艾滋病”,AIDS)流行的前兆1。人们也很快注意到艾滋病还和侵袭性B细胞淋巴瘤的高发病率相关。由于艾滋病的定义已经具体化,因此在感染了人类免疫缺陷病毒(HIV)的患者体内出现的卡波西肉瘤、侵袭性B细胞淋巴瘤和宫颈浸润癌均可视为艾滋病界定癌症(AIDS-defining cancers)2。现在已知还有其他癌症也和HIV相关(表1)。本文用HIV相关性癌症一词来统称这些在HIV感染患者中发病率增高的癌症大群(包括艾滋病界定癌症和非艾滋病界定癌症)。此外,HIV感染者也可能罹患偶发癌症。


Robert Yarchoan, M.D., and Thomas S. Uldrick, M.D.
From the HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD. Address reprint requests to Dr. Yarchoan at the National Cancer Institute, 10 Center Dr., Rm. 6N106, MSC1868, Bethesda, MD 20892, or at robert.yarchoan@nih.gov.



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